What does PR mean on a prescription?
PR means by the rectum — a suppository, enema, or rectal gel, rather than something swallowed.
- Means:
- by the rectum
- From:
- per rectum
- Type:
- How to take it
- Also written:
- pr, p.r., PR
What it means in practice
The rectal route is used when someone cannot swallow or is vomiting, when a medicine needs to act locally, and for some fever and seizure treatments in children. In clinical notes PR can also be shorthand for a per-rectum examination, so context matters.
Example on a prescription
Paracetamol 500 mg PR Q6H PRN fever
Insert one 500 mg paracetamol suppository rectally no more often than every six hours, when there is fever.
Commonly confused with
- POPO is by mouth. PO and PR differ by one letter and describe completely different routes.
- PRNPRN is as needed, a frequency instruction rather than a route.
Worth knowing
PO and PR are only one letter apart. If a label is handwritten or unclear, confirm the route before giving the medicine — especially for a child.
Frequently asked questions
What does PR mean on a prescription?
Give it rectally — as a suppository, enema or rectal gel.
Why would a medicine be given PR instead of PO?
Usually because the person cannot swallow or is vomiting, or because the medicine needs to work directly in the lower bowel.
Related abbreviations
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This page explains prescription notation for general information. It is not medical advice and does not replace your prescriber or pharmacist. If a label is unclear or differs from what you were told, check with your pharmacy before taking the medicine.