What does SQ mean on a prescription?
SQ means subcutaneous — an injection into the fatty layer just under the skin, such as insulin or a weekly GLP-1 medicine.
- Means:
- subcutaneous
- Type:
- How to take it
- Also written:
- sq, subq, SubQ, SC, s.c.
What it means in practice
Subcutaneous tissue has less blood flow than muscle, so absorption is slower and steadier — useful for insulin. Common sites are the abdomen, outer thigh and back of the upper arm, and rotating the site helps avoid lumps.
Example on a prescription
Insulin glargine 10 units SQ QHS
Inject 10 units of insulin glargine under the skin each night at bedtime.
Commonly confused with
- IMIM is deeper, into the muscle, and absorbed faster.
Frequently asked questions
What does SQ mean on a prescription?
Inject it subcutaneously — into the fat just under the skin.
What is the difference between SQ and IM?
SQ is into the fat under the skin and is absorbed slowly and steadily. IM is into muscle and absorbed faster.
Related abbreviations
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This page explains prescription notation for general information. It is not medical advice and does not replace your prescriber or pharmacist. If a label is unclear or differs from what you were told, check with your pharmacy before taking the medicine.